BIOCHEMISTRY(1)

Biochemistry(1) is the first semester of the undergraduate series, which provides students with and introduction to biochemistry at the advanced undergraduate level. Biochemistry(1) introduces basic biochemistry concepts including protein structure, purification, enzyme kinetics and mechanisms, lipids and membranes, and biosynthesis of nucelic acids(DNA and RNA)

By the end of the course, the students should be able to demonstrate fundamental knowledge and understanding in the following core areas. 1.Aspects of protein structure: The principles of globular protein structure. The behaviour of proteins in solution and the principles of molecular recognition. The principles of membrane protein structure determination. 2.Enzyme kinetic behaviour and mechanisms. Intermediates in enzyme-catalysed reactions and their investigations. 3.Mechanism and control of DNA transcription in animals. Transcription initiation in eukaryotes is a highly complex, multi-step process. The role of general transcription factors in mediating the various steps in transcription initiation will be described. Models for about the appropriate temporal and spatial control of gene expression will be discussed. 4.DNA damage repair, and integrity, immortalisation. The molecular basis of the processes that occur in DNA recombination and repair process. 5.Build on their knowledge and understanding in tackling more advanced and specialised courses, and more widely to pursue independent, self-directed and critical learning.

Attendance: Attendance at lectures, recitations, and problems sessions is expected. To encourages better attendance, a point system is implemented. If a student is absent, or comes in late, a tardy point is automatically applied to his/her record. (Absence = 0.6 point deduction, late show-up = 0.2 point deduction) Continued absences will detract from student's final grade. If a student has a valid reason for missing class such as university-sponsored activity or death of the family, the instructor will assist him/her in obtaining information and materials he/she may have missed. Also failure to take an exam in the alloted time will result in a zero for that exam. Exceptions will be made for exams which are missed because of:  University-sponsored activities. You must make alternative arrangements with me at least a week in advance.  Documented medical absence.  Death in the family.  Full-time emplyment acknowledged and approved by Keimyung University. Students who attend at Biochemistry lecttures are asked to turn off their cell phones immediately when they enter the classroom. The 3 strike rule will be employed if student (s) choose to ignore Cellphone policies and he/she will get deduction from class participation points.

Lecture notes will be posted. These notes are based on the textbook, so most of the figures and information they contain can also be found in textbook. These notes contain most figures discussed during lecture and are designed to aid students' note taking during lecture and while reading the text. It is highly recommended that students print these lecture notes and read the assigned reading in the text prior to lecture, taking notes while they read. Then bring the notes to lectures to help fill in areas that were confusing when they first read them in the text.

At the conclusion of this course successful students will be able to familiarized with the major aspects of biochemistry.
For students in Natural science fields, studying biochemistry is especially important for those, who hope to enter a career in drug discovery and some form of biotechnology.